Selank is a synthetic peptide derived from the naturally occurring human tetrapeptide tuftsin. It is primarily used for its nootropic, anxiolytic, and neuroprotective properties. Selank acts by modulating the brain's neurochemical balance and has been studied for its effects on mood, cognitive function, and the immune system.

1. Modulation of Neurotransmitter Levels:

   • Selank influences the metabolism of serotonin, dopamine, and norepinephrine, contributing to mood stabilization and improved focus.

   • It enhances the release of gamma-aminobutyric acid (GABA), producing anxiolytic (anti-anxiety) effects.

2. Regulation of Cytokine Levels:

   • It has immunomodulatory properties, reducing pro-inflammatory cytokines and promoting an anti-inflammatory profile.

3. Stimulation of Brain-Derived Neurotrophic Factor (BDNF):

   • Selank increases the expression of BDNF, which supports neurogenesis, synaptic plasticity, and overall brain health.

4. Inhibition of Enkephalin-Degrading Enzymes:

   • This helps maintain higher levels of enkephalins, endogenous peptides that reduce pain and anxiety.

5. Stabilization of the Enkephalinergic System:

   • Selank enhances the brain’s capacity to adapt to stress and improve emotional regulation.

1. Serotonin Pathway:

   • Selank balances serotonin levels, which is crucial for mood regulation, anxiety reduction, and general well-being.

2. Dopaminergic Pathway:

   • Dopamine modulation contributes to enhanced motivation, focus, and cognitive processing.

3. Hypothalamic-Pituitary-Adrenal (HPA) Axis:

   • Selank can help regulate the stress response by modulating the activity of the HPA axis.

4. Immune Pathways:

   • Selank interacts with immune cells to reduce inflammation and enhance overall immune function.

1. Cognitive Enhancement:

   • Improves memory, focus, and learning ability.

   • Supports faster information processing and retrieval.

2. Anxiolytic Effects:

   • Reduces symptoms of anxiety without sedative effects.

   • Useful for managing stress and social anxiety.

3. Mood Stabilization:

   • Promotes emotional balance and reduces depressive symptoms.

4. Neuroprotective Properties:

   • Enhances brain resilience to oxidative stress and neuroinflammation.

   • May reduce the risk of neurodegenerative conditions.

5. Immune Support:

   • Improves immune system functioning and reduces inflammation.

6. Stress Reduction:

   • Modulates stress responses, making it easier to cope with challenging situations.

Anxiety and Stress

• Persistent anxiety or feelings of nervousness and worry.

• Overwhelmed by daily stressors, leading to difficulty concentrating or functioning effectively.

• Constant feelings of unease or irritability without a clear cause.
  

Cognitive Function and Focus Issues

• Struggling with mental clarity, focus, and concentration, especially during work or tasks.

• Mental fatigue or brain fog that makes it hard to think clearly or make decisions.

• Difficulty retaining information or experiencing memory lapses.

  
  

Low Motivation and Mental Fatigue

• Lack of motivation to complete tasks, both personal and professional.

• Decreased energy and enthusiasm for activities that were once enjoyable.

• Feeling mentally drained or exhausted even after rest.

  
  

Mood Fluctuations and Emotional Instability

• Unpredictable mood swings that make emotional regulation challenging.

• Feeling down or unbalanced emotionally, leading to low self-esteem.

• Difficulty dealing with stress or emotional setbacks in a healthy way.
  

Sleep Disturbances

• Insomnia or poor-quality sleep caused by heightened stress and anxiety.

• Struggling to unwind and relax before bedtime.

• Waking up feeling unrefreshed, impacting overall productivity and health.

Motivation to Improve Mental Health

• Frustration with not finding an effective solution for mental clarity, mood regulation, and stress management.

• Desire for cognitive enhancement without turning to stimulants or other harsh substances.

Selank peptides address these pain points by reducing anxiety, boosting mood, improving cognitive function, and enhancing focus while promoting a sense of calm without the side effects of traditional medications.

1. Standard Dosage:

   • The typical dose is 250–500 mcg per administration.

   • It can be taken 1–3 times per day, depending on the individual’s needs and the healthcare provider’s recommendation.

2. Administration Routes:

   • Subcutaneous Injection: Rarely used but can be an alternative.

3. Duration of Use:

   • Selank can be used in cycles (e.g., 5 days on, 2 days off) or continuously for several weeks.

   • Long-term use should be monitored to avoid receptor desensitization.

Dosing at 250 mcg every morning will last 200 days. That is less than $2.2/day at the recommended dose.